SOVEREIGN PROOF ENGINE

Total Predictions
27,485,188
Unique Scaffolds
5,433,799
Blockchain Batches
2,158
Enriched Molecules
15,341,122
VAULT-Tier Compounds
195,742
Top 0.5% — sovereign-grade binding affinity
Prediction Velocity
163,920
New predictions in last 24 hours

KNOWN DRUGS DISCOVERED

Axiom independently identified these pharmaceutical compounds — validating model accuracy

NSAID

Aspirin

1.0000
Binding Score
NSAID

Ibuprofen

1.0000
Binding Score
Polyphenol

Caffeic Acid

1.0000
Binding Score
Purine

Uric Acid

0.4533
Binding Score

MOLECULAR ANALYTICS

Binding Score Distribution
LogP Distribution
SCINS Traffic Light
Lipinski Violations

COMPOUND QUALITY FUNNEL

ENRICHMENT PASS RATES

Lipinski Pass
35.3%
Veber Pass
3.4%
PAINS Clean
32.4%
Lead-like
0.3%

QUALITY PIPELINE

DRUG-LIKENESS PROFILE

Drug-likeness Radar
ADMET Traffic Light
Pharmacokinetic assessment (distinct from SCINS structural classification)

DATA TIER BREAKDOWN

DISCOVERY 10,720,467
ENTERPRISE 9,171,834
PROFESSIONAL 7,397,145

CATEGORY BREAKDOWN

Category Counts
peptide-like 16,701,551
drug-like 10,760,804
fragment 22,833

TOP MURCKO SCAFFOLDS

Scaffold structures are available through partnership engagements — labs@smartledger.solutions

# Scaffold Count Avg Binding
1 🔒 partnership-gated 33,329 0.5559
2 🔒 partnership-gated 30,015 0.3759
3 🔒 partnership-gated 29,706 0.4504
4 🔒 partnership-gated 25,034 0.4941
5 🔒 partnership-gated 22,690 0.4461
6 🔒 partnership-gated 13,305 0.4424
7 🔒 partnership-gated 11,105 0.2746
8 🔒 partnership-gated 10,639 0.5851
9 🔒 partnership-gated 9,748 0.2869
10 🔒 partnership-gated 9,217 0.4122
Partnership Access
Compound dossiers, ADMet profiles, scaffold data, and bulk exports are available through partnership engagements with our research team.